Vitro fertilization.

In vitro fertilization (IVF), or in vitro fertilization, is a revolutionary method of assisted reproductive technology that has given great hope to infertile couples. Currently, it can be considered the most effective method of treating infertility. Sometimes with the help of IVF it is possible to get pregnant even in the most hopeless situations.
In vitro fertilization (IVF) is an assisted reproductive technique that allows women to conceive with a diagnosis of infertility. Modern IVF clinics in Moscow operate according to the following algorithm:

- the egg is removed from the body of a woman;
- the egg is artificially fertilized;
- the embryo develops in an incubator for 2-5 days;
- the embryo is transferred to the uterus.
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IVF clinics in Russia have high-quality technical equipment and a staff of trained specialists to perform in vitro fertilization in full compliance with the required regulations. Today it is the most popular procedure of the ART category (assisted reproductive technologies), annually more than 4 million women become pregnant this way.
IVF stages.

1. Hormonal preparation.
Hormone preparation is an injection of intramuscular or subcutaneous injections to stimulate ovarian activity, due to which several eggs mature at the same time, which are subject to further fertilization. This greatly increases the chances of a woman becoming pregnant.

2. Ultrasound control.
Starting from the day prescribed by the doctor, every morning you should come to the clinic. An ultrasound is performed on the woman, which allows her to monitor the process of follicular maturation and monitor the condition of the uterus and ovaries. Follicles are counted and measured. If the examination shows that the follicles have reached the required size and degree of maturity, in the evening the patient is injected with choric gonadotropin (CG), which causes ovulation. The exact moment of egg extraction occurs on the morning of the second day after the injection - after 34-35 hours.

3. Fertilization.
On the day of the "release" of the eggs, the partner donates sperm for fertilization. Subject to certain conditions, you can bring sperm with you. Egg collection takes place in the operating room next to the laboratory where fertilization will take place. The patient is under the control of ultrasound in the gynecological chair. Through the vagina, the doctor punctures the follicles, and then the eggs are removed from the obtained follicular fluid and placed in pre-prepared, labeled capsules with the culture medium. Anesthesia for puncture for most women is not required, but if desired, you can perform a puncture under anesthesia. In the laboratory, semen is diluted with a special culture medium and becomes ready for fertilization. after a few hours, a drop of sperm is added to each egg, the mixture is placed in an incubator overnight.

The next day, under a microscope, it is checked whether fertilization has occurred, if so, how many eggs have been fertilized. Fertilized eggs contain two nuclei, in one nucleus are the chromosomes (hereditary material) of the mother, the other is formed from the sperm penetrated into the egg and contains the father's chromosomes.

4. Transfer of the embryo into the uterine cavity.
Embryo implantation in the uterine cavity also occurs in the operating room, in the gynecological chair. This procedure is painless, it can be compared with a conventional gynecological examination. A thin, soft catheter with the eggs in it is inserted through the uterine pharynx into the uterus, then fertilized eggs with a drop of culture medium are slowly released from the catheter. After half an hour spent lying down, a woman can go home and continue a normal life. Sexual life is allowed from the next day.
The best IVF clinics in Russia are located in Moscow, the procedure is performed at the modern level and gives the greatest effectiveness among similar technologies - a successful pregnancy develops in more than 33% of cases. Given the possibility of becoming pregnant with a diagnosis of infertility, the price of the procedure is low.

However, even in the best IVF clinics in Moscow, this is one of the most technically complex medical solutions, the implementation of which is impossible in a number of situations. Direct contraindications to the procedure:

- mental pathologies that are contraindications to pregnancy and childbirth;
- pathological changes in the uterus, making embryo replanting impossible during the procedure;
- benign tumors in the ovaries and uterus, any malignant tumors;
- pathologies in acute form, accompanied by acute inflammatory processes.

IVF clinics in Moscow, as a rule, do not reveal contraindications to the procedure for men, good enough spermogram indicators.
There is no rating of the best IVF clinics in Moscow, because such a rating cannot be compiled by an objective indicator. Moreover, all the clinics providing such services demonstrate equal effectiveness of the procedure.

Auxiliary hatching.

After transfer to the uterus, the fertilized egg continues to divide rapidly, while being in the fetal membrane. In order for pregnancy to occur, the embryo must leave it after a few days to attach to the uterine mucosa.

In accordance with the latest technique, the chances of ultimate success can be increased if a tiny hole is made in the fetal membrane immediately before implantation of the embryo. This micromanipulation is performed using a specially designed laser device, or mechanically. The method is called "auxiliary hatching" and is used primarily in cases where, in previous attempts, the fertilized egg did not take root in the uterus.